The best way I can show this is with games - which are entirely unplayable. Here is a video of what is happening:
https://www.youtube.com/watch?v=Rqb5qPencVE
Notice that it happens every time I click.
I have another video of it happening with Half Life and Dark Souls (but its not as clear that it happens on click in that one) This happens with every application, its just far more visual with fullscreen applications.
This never happened before I started having issues with some extensions not installing in chrome (fixed that...), and I reached out to a friend from university who sent me an exe that he pulled from a forum on google that installed a shit-ton of adware into my system.
So, after I realized what was happening, I rebooted into Ubuntu and cleared my %temp% and deleted a few suspicious folders from c:\programdata. I then rebooted into safe mode, uninstalled everything that I didn't put there and that wasn't supposed to be there as a dependency, CCleaned the system, and ran two virus scans and removed everything that came up. The system is fine adware-wise now, no programs that I can find in the program files/programdata/%temp% or anywhere else. (Or through the control panel for that matter)
I checked my graphics drivers, and I tried it on an external (in the video) and on my main monitor.