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Is there some sort of emulator or software layer that will let me run Windows executables (exe) in Mac OS X 10.5?

I am not looking for Boot Camp or Parallels or any OS virtualization. I want something like WINE on Ubuntu.

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up vote 8 down vote accepted

There are ports of WINE for OS X from other vendors (The WINE project does not make OS X binaries themselves), but remember, WINE Is Not an Emulator ;)

Did I mention how much I love recursive acronyms? :)

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You might also try CrossOver, which is WINE with support. There's a free trial.

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+1 You can use CrossOver to run executables, but the results might be less than spectacular; not everything runs all that great. For me, CrossOver was good enough though. – alex Jan 6 '10 at 7:53

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