I have following users in my registry.
s-1-5-18
s-1-5-19
s-1-5-20
S-1-5-21-3580036505-2828148361-1391708163-1001
S-1-5-21-3580036505-2828148361-1391708163-1001_Classes
Is it a virus or system users?
There is also a folder which contains folders of the above names and there are data files.
This folder can be deleted by shift + delete (Not only delete). Created again when something is copied / moved or deleted.