I recently was forced to destroy everything in the ~/Library/Keychains folder on my Mac (we're using Active Directory users and I've always had keychain troubles when it's time to change the password). I've done this plenty of times before.
However this time, Chrome is no longer saving passwords at all. It still prompts me if I want to save them and occasionally autofills a name (though I suspect that's Mac OS rather than Chrome).
I've already checked and both boxes under "Passwords and Forms" are checked in settings. There are no sites listed under "Manage Passwords." I've also checked to make sure both the Local Items and Login Items keychains are unlocked in Keychain Access.