I actually recommend getting Visual Studio Express (Free) and creating an interface of your own.
I recommend this because it doesn't involve third parties, and because it's free and very easy.
The general idea would be to:
- create a VB project,
- set the window to no titlebar,
- set the window position fixed to X Y on some place on your screen,
- and put the .exe on your desktop near the place where the window position was set.
A completely unstyled window with buttons created in VS:
Which, after removing the title bar, adding more buttons, and setting images on those buttons, you can get something like this:
Each button would have a handler that looks like so:
Private Sub Button3_Click(ByVal sender As System.Object, ByVal e As System.EventArgs) Handles Button3.Click
It's really easy code, it's a free IDE, everything is drag-and-drop.
What you get is full customization, no third parties, and some VB experience!