I have two Thunderbolt Displays plugged into my laptop, and as a consequence, two additional audio devices become available. I find that even when I configure one display as the default output and input device, the actual behavior I get is usually unpredictable and rarely reflects the configuration I set.
I will never use the mic or audio on one of the displays. Can I somehow delete the device or otherwise deactivate it from OS X? Some sort of equivalent effect to what you get in Windows when you go to Device Manager, right-click the device, and selecting "Disable" (or whatever the text is, going from memory here)? Maybe a plist I can edit somewhere?