When attempting to install a Microsoft-signed ClickOnce application, an error appears stating "Your administrator has blocked this application because it potentially poses a security risk to your computer" and "Your security settings do not allow this application to be installed on your computer".
As the administrator who would have set said policies, I cannot for the life of me figure out why this is being blocked for just one user and not other users whose PCs are based off the same image and why it works for other users who should be enjoying the same privileges as the user who is receiving the following message. Note that the exact same domain group policies are applied to this user that is experiencing the error and to users who are not receiving the error.
Even attempting to run the application "as an administrator" does not solve the issue. The event logs show no errors, and I cannot otherwise find any logs to help diagnose the issue.
What local policies or settings would allow or deny this application?