I get major delays in some scenarios using my keyboard and sometimes also mouse. Using (browser-like?) apps e.g. Windows start menu, Firefox, Chrome in Windows 10, it can take seconds or minutes for what I type to appear on screen (including this question!). Typing a lot of characters usually results in a few being displayed before a long delay, then all the remaining characters typed are spat out. Sometimes the problem is not apparent at startup, but almost inevitably develops at some point and then does not resolve without a reboot. Usually it does not affect performance in other programs e.g. Ms Word. This isn't a new issue.
I've recorded an example using Windows Performance Recorder https://www.dropbox.com/s/cr05fvvi0cp0q0s/TOMPC.03-21-2018.12-44-41.zip?dl=0
Having tried to look at the analysis and previously looking at task manager I've wondered whether Cortana is somehow involved. I tried disabling it through the registry but I think that's the communication with microsoft and anyway it didn't help.
System is:
Windows 10 Home 1709 16299.309
Intel i5-2500K
Asus PBZ77-V LX
USB wired keyboard (I've also used a different wireless keyboard)
Hard drive SMART info from HDTune:
HD Tune: Corsair Force 3 SSD Health
ID Current Worst ThresholdData Status
(01) Raw Read Error Rate 90 90 50 223712322 Ok
(05) Reallocated Sector Count 100 100 3 0 Ok
(09) Power On Hours Count 85 85 0 13512 Ok
(0C) Power Cycle Count 100 100 0 984 Ok
(AB) (unknown attribute) 0 0 0 0 Ok
(AC) (unknown attribute) 0 0 0 0 Ok
(AE) (unknown attribute) 0 0 0 96 Ok
(B1) (unknown attribute) 0 0 0 4 Ok
(B5) (unknown attribute) 0 0 0 0 Ok
(B6) (unknown attribute) 0 0 0 0 Ok
(BB) (unknown attribute) 100 100 0 0 Ok
(C2) Temperature 30 30 0 1966110 Ok
(C3) Hardware ECC Recovered 120 120 0 223712322 Ok
(C4) Reallocated Event Count 100 100 3 0 Ok
(C9) TA Counter Detected 120 120 0 223712322 Ok
(CC) Soft ECC Correction 120 120 0 223712322 Ok
(E6) GMR Head Amplitude 100 100 0 100 Ok
(E7) Temperature 100 100 10 0 Ok
(E9) (unknown attribute) 0 0 0 8192 Ok
(EA) (unknown attribute) 0 0 0 6458 Ok
(F1) (unknown attribute) 0 0 0 6458 Ok
(F2) (unknown attribute) 0 0 0 12056 Ok
Power On Time : 13512
Health Status : Ok
HD Tune: WDC WD2003FZEX-00Z4S Health
ID Current Worst ThresholdData Status
(01) Raw Read Error Rate 200 200 51 0 Ok
(03) Spin Up Time 145 137 21 11708 Ok
(04) Start/Stop Count 98 98 0 2832 Ok
(05) Reallocated Sector Count 200 200 140 0 Ok
(07) Seek Error Rate 200 200 0 0 Ok
(09) Power On Hours Count 89 89 0 8653 Ok
(0A) Spin Retry Count 100 100 0 0 Ok
(0B) Calibration Retry Count 100 100 0 0 Ok
(0C) Power Cycle Count 100 100 0 435 Ok
(C0) Power Off Retract Count 200 200 0 73 Ok
(C1) Load Cycle Count 200 200 0 2758 Ok
(C2) Temperature 113 102 0 39 Ok
(C4) Reallocated Event Count 200 200 0 0 Ok
(C5) Current Pending Sector 200 200 0 0 Ok
(C6) Offline Uncorrectable 200 200 0 0 Ok
(C7) Ultra DMA CRC Error Count 200 200 0 0 Ok
(C8) Write Error Rate 200 200 0 0 Ok
Power On Time : 8653
Health Status : Ok