Greetings to the community, I recently tried to open my VirtualBox (windows 10 host OS) after approximately 3-4 months (when everything was perfect). Unfortunately, now the VirtualBox is unable to get started and I'm getting the following error message

Failed to acquire the VirtualBox COM object. The application will now terminate.

Completely failed to instantiate CLSID_VirtualBox: ERROR_FILE_NOT_FOUND 0x80070002.

Result Code: 
ERROR_FILE_NOT_FOUND 0x80070002 (0x80070002)
IVirtualBoxClient {d2937a8e-cb8d-4382-90ba-b7da78a74573}

error message

What I have tried so far is:

  1. Uninstall the virtualbox installation

  2. Re-install

  3. Reboot


I have searched on the web for a solution but did not find anything really enlightening. Maybe this was caused due to a corrupted file on my system? Could you please provide an alternative workaround? I just do not want to lose my existing VMs. Thanks in advance :)

PS: I don't know if this is related, but I have previously used Vagrant on my system, I mention that because it would not come to me as a surprise if the Vagrant corrupted something related to the VirtualBox.

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  • Generally, reinstallation solved this same issue in my case. Did you see any error code during installation? Did you delete any file from the installation folder? – Biswapriyo Dec 5 at 20:48
  • @Biswapriyo thanks for your reply, no I did not see any error during the installation neither I deleted any file from the installation folder, maybe is a corrupted in the registry file? – NickAth Dec 5 at 22:16
  • Run these two commands as administrator: 1. reg query "HKEY_CLASSES_ROOT\Interface\{D2937A8E-CB8D-4382-90BA-B7DA78A74573}\ProxyStubClsid32" /VE 2. reg query "HKEY_CLASSES_ROOT\CLSID\{0BB3B78C-1807-4249-5BA5-EA42D66AF0BF}\InProcServer32" /VE. Replay with what did you see? – Biswapriyo Dec 6 at 14:35
  • @Biswapriyo Reply from command 1) reg query "HKEY_CLASSES_ROOT\Interface\{D2937A8E-CB8D-4382-90BA-B7DA78A74573}\ProxyStubClsid32" /VE HKEY_CLASSES_ROOT\Interface\{D2937A8E-CB8D-4382-90BA-B7DA78A74573}\ProxyStubClsid32 (Default) REG_SZ {0BB3B78C-1807-4249-5BA5-EA42D66AF0BF} Reply from command 2) reg query "HKEY_CLASSES_ROOT\CLSID\{0BB3B78C-1807-4249-5BA5-EA42D66AF0BF}\InProcServer32" /VE HKEY_CLASSES_ROOT\CLSID\{0BB3B78C-1807-4249-5BA5-EA42D66AF0BF}\InProcServer32 (Default) REG_SZ C:\Program Files\Oracle\VirtualBox\VBoxProxyStub.dll – NickAth Dec 6 at 14:57

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