Similar to this question I would like to have another folder actually store my files that visibly show on my desktop. The reasoning is I have a large HDD for file storage and a smaller SSD with the OS that I would rather not clutter up with files.
Your problem is quite easy, and many plenty of people are using difference storage for OS(ex, a M.2, or a SSD) then another storage for basically everything(HDD). You'll just have to read each installation that you'll do.
Your PC setup will basically have a Master and Slave disks, Master is the SSD, which in booting, will be accessed by your CPU for OS information, and your HDD Slave, to store all other clutters.
While installing, you just have to make sure that you don't click next, read everything, and when you reach the point to where will you install the software, choose. After installing, those softwares that you want to access to will have shortcuts in your desktop.
BUT, If your thinking, of replicating EVERYTHING from a folder in your HDD, to your desktop... I guess you could create shortcuts for those files...
Alright, I figured it out.
When you open up My PC you can right click on Desktop > Properties > Location tab. The middle button on that tab is a "Move" option which lets you select another folder - in my case one named "Desktop" on my other drive - and then moves anything on your current desktop to the new one and changes the target folder of the desktop.