When you use the function (fn) key on a MacBook Pro, it acts like a shift key (only works while you hold it) as opposed to a toggle. Is there anyway to change this? Preferably with a native setting, but I'd also consider 3rd party software.
It looks like Palua might help you achieve what you want, $1 from the Apple Store.
Just as an addendum, since you haven't specified Mac OSX, if you use bootcamp (for running Windows on a mac machine) the FN key behaves EXACTLY as I wished it would on OSX:
On Bootcamp Windows, when you hold a modifier key + any function key it will act as F# already - for that you don't need to hold the FN key. While just pressing them will work as shown on the button.
If you press, let's say, F1 and F2, which are brightness up and down, it will act on brightness, if you press F10, it will mute, and so on, just like the pictures on the keys, and how you would expect.
But If you hold ALT+F4, for instance, it will close an application rather than launching the Dashboard. Ok, there's no dashboard in bootcamp, but you get the point.