Where is the Chrome settings file?
Inside this folder there is a Temp folder, several global files, and then a folder for each profile. Most settings are profile-specific, so you'll probably want to look in there.
There's probably just one profile, "Default". If you delete it, you'll lose all your settings, history, cookies, saved passwords, bookmarks, extensions, etc. Chrome will simply recreate it the next time you run it, though.
In OS X: