I went to open Outlook 2007 on my Windows 7 32bit machine and it came up with this error:

Cannot start Microsoft Office Outlook. Cannot open the Outlook window. The set of folders cannot be opened. The information store could not be opened.

I have deleted and created a new profile in Control Panel > Mail but it still doesn't want to work properly but it still comes up with this message.

Thanks in advance.


4 Answers 4


Just had it happen to me this morning. (Win7 x64, Outlook 2007). The message can be caused by a number of issues like a compatibility setting or a corrupted outlook profile file. In my case, I had to run the following at a command prompt:

Outlook.exe /resetnavpane

The technical issues surrounding the Navigation Pane can be found at Microsoft's Support site KB2022778.


Have you tried safe mode?

a) Hold Ctrl and click Outlook from start menu


b) "Outlook.exe /safe" from command prompt

  • Yep I tried that but it came up with the same thing. I managed to sort it. Thanks anyway
    – deanpcmad
    Commented Jun 9, 2010 at 13:49

Have sorted it. Changed the .pst in Control Panel > Mail and created a new default pst file and it seems to be working fine for some reason.


I tried hard to fix it but it not work for me. Then I did this and it worked for me


  1. Uninstall Program Microsoft office 2007
  2. restart
  3. Install new Microsoft office 2010
  4. Set new outlook again

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