Sometimes when I, for example, extract a folder from an archive with WinRAR to the desktop, the folder gets placed in the top left corner of the desktop and messes up the ordering of other icons. But when I move the folder to a proper position and move the other icons back to place and then extract another folder, it works normally. WinRAR is not the only program this happens with though. Seems like it can happen with any program that creates a folder or file on the desktop.
This happens randomly and I havent found any way to reproduce it reliably. Dragging items to the desktop works normally still.
I have always had "Align icons to grid" enabled and "Auto arrange icons" disabled. This problem started occuring only recently. I'm using Windows 10 Pro, build 18363. I'm not 100% sure but I suspect that this started happening after installing Windows update KB4556799 or KB4552931 as those are most recent while others were installed a month ago.
KB4556799 and KB4552931
were both released last week not a month ago. If you suspect those updates you should temporarily uninstall them. Your illustration does not clarify your problem, what I see in the illustration, is typical behavior.