These keys are registered through explorer and that is the first thing that starts. Unfortunately its not possible to do a hack to get these shortcut keys to be used for anything else.
The first program that claims a hotkey basically gets to use it. You would therefor have to kill explorer entirely, claim the hotkey and then launch explorer. This however is not an option.
I wanted to use CTRL-ALT-SHIFT-WIN+w which is used for office and when you press it, it opens a website. I tried everything in my power to get that key, but its just not working reliably and cleanly. I can basically get the key, but then explorer doesn't start. If I do it manually, it will work, but I don't want to do it every single day.
So long story short: no, use a different key.