From http://www.playtool.com/pages/psuconnectors/connectors.html#atxmain20 :
You can plug a 20 pin ATX power cable into a motherboard with a 24 pin
ATX connector [...] The 24 pin motherboard connector is actually just
the 20 pin connector with 4 extra pins added on the end. The original
20 pins were unchanged. The extra 4 pins are not separate rails.
They're just extra lines to provide more current to the same rails.
[...] I've never heard of exceptions and it doesn't make sense for
motherboard makers to create any.
and...
A 20 pin power cable only fits into one end of a 24 pin motherboard
connector so you can't insert it incorrectly.

however, it appears that there is no current limiting on a 20 pin ATX PSU, as I assumed there would be...
They added those extra 4 pins for a reason. When you plug a 20 pin
cable into a 24 pin connector you're not providing the extra current
carrying capacity which may be needed by the motherboard. If your
motherboard's current requirements are low enough then it will work
properly with only a 20 pin power cabled plugged in. But if the
motherboard draws enough current, then you can overheat the 20 pins
you're using on the 24 pin connector. I've seen enough pictures of
burned ATX main connectors to assure you that this happens. [...]
Connectors really do get hot if you overload them so the safest thing
to do is use a real 24 pin power supply on a motherboard with a 24 pin
connector. Note that your 24 pin machine may work fine with a 20 pin
power supply until you add a PCI Express card later on down the road.
PCI Express cards can draw up to 75 watts through the motherboard
connector so adding an expansion card can substantially increase power
draw through the main power cable.
Lastly, as an aside:
If you have an ATX power supply with a 24 pin main cable, it's okay to plug it into a motherboard with a 20 pin connector.
