I just bought an ASUS M5A88-V EVO motherboard and it says that it supports up to 16GB of RAM. I also bought two 8GB sticks of memory. Will this work with my motherboard or do I need to get four 4GB sticks if I want 16GB?
Based on the results below:
You are limited to 4GB x 4. i.e. It doesn't look like your board supports 8GB sticks.
Did you check the manual? Page 2-11 is pretty clear about what you can use:
2.4.2 Memory configurations
You may install 512MB, 1GB, 2GB, and 4GB unbuffered ECC and non-ECC DDR3 DIMMs into the DIMM sockets.
You will need to return your 8GB sticks and exchange them for 4GB sticks.
Always a good idea to read the manual first. This motherboard's specs are at: http://www.asus.com/Motherboards/AMD_AM3Plus/M5A88V_EVO/#download
The section on memory configurations, says: You may install 512MB, 1GB, 2GB, and 4GB unbuffered ECC and non-ECC DDR3 DIMMs into the DIMM sockets.
So unless the manual was written before 8GB DIMMs were available and they opted not to mention the then hypothetical sizes, looks like they are not supported. Of course, they still may work - either with their complete 8gb range or just 4gb of them. You should update your question when you discover the bleeding edge results.