I've got a Lenovo X230 Tablet that suddenly lost the ability to track the pen. It acts like the pen is always in the upper left corner of the screen. The touch screen portion also failed at the same time, but was restored by a reboot. Unfortunately, rebooting has not helped the pen interface. All Lenovo drivers are current. I've been unable to locate any recalibration utility amongst the Lenovo software.
Don't know if this helps, but this names the utilities used to calibrate on this exact model: