Some of my old DOS programs require the following command line in config.sys or config.nt:
device=ansiibm.sys
How do I accomplish this in DOSBox? I've tried putting this line in the config options file--didn't work.
It looks like there is no direct config.sys emulation in DosBox. One of the developers was asked about it on SourceForge. He said that "You can however boot a version of dos inside dosbox (using the boot command) in that version you can put what you like."
I looked into the Boot Command, and it uses DOS drive images, if you have any. This replaces the DosBox directories, so it may not be what you're looking for.
However, I found some interesting information here, regarding MSDOS emulation in Windows XP. I didn't know this before, but you can set up custom config.sys and autoexec.bat files within a shortcut to a command prompt. It even allows you to change the hardware timer emulation, so that old DOS programs (games) don't operate way too quickly :)
I hope some of this helps!