There are many benchmarking and stress testing software tools that could be used to get the CPU and GPU working as hard as it would ever work, possibly working harder, and using more power than your computer would ever in its life.
With these benches and stress tool or combinations of, you could test your system to see if the PSU can hold up under the load.
As pointed out by n.1 in the comments, these stress tests can also crash a system that would work normally, even without the PSU having anything to do with it. Because of that some effort and understanding of what the stress test does and is doing, and how you apply it would be important.
Disclaimer: understand before doing any of this.
With an overclock testing tool like OCCT, it provides for a capability to beat on the CPU and GPU at the same time, flooding both with work to do, and raising your power consumption while the test is running. OCCT (and similar) is one way to test a (usually) fully operational system using lots of power from the PSU.
I have used Benching combinations to accomplish the same thing. run furmark, and "prime" at the same time, combinations of benching programs, to cause the whole system to have to work as hard as possible. When the system is fully functional (again).
Used seperated there are many benching and testing program/utilities out there that stress the heck out of specific aspects of the components.
Prime (and similar) with small will stress ram, prime with large will stress cpu (more than ram).
Furmark (and similar) with render will stress the gpu, furmark with artifact testing will stress the video ram.
All of the above methods can be harsh on the whole system and system cooling (cpu, ram, gpu and its ram) must be observed when using them, so to be used with great caution and awareness. Doing that on a laptop, when a laptop was not designed to cope with it could be a very bad idea.
Applying a voltmeter or volt reading software at the same time as running any of it, checking the PSU fans, and heat comming out, for seeing if it was coping.
Screen flicker could be simple V-sync issues, changes in clocking of the video ram (when gpu is stepping), and even a lcd screen that is blipping. I have presented ways to use power like the title says, but it is less likely to solve or even be the problems stated. To test for v-ram clocking flicker lock your gpu clock to a single speed (even a low one), and test again.
USB charge: When possible I always concider the costs of the Whole computer, vrses the cost of a good (even expencive oem) charger that runs seperated from the wall socket. Unless required to connect I prefer to setup some charge method for portable devices that does not require the $$$ computer. My motherboard even has "charger" ports & software for boosting specific ports, I still prefer to charge seperated.
When assembling a system with a high power GPU, it can be very usefull to understand the "rails" (seperated curcuits) of the 12V if it is not single rail, to distribute the seperated curcuit power as wisely as possible. see Ntoskml comment about finding good info online , and breakdowns on the rail system for your PSU , or understanding the connection layout better via the manuel or data provided on the PSU, before connecting.