I am running Process Explorer version 16.02 on Windows 7 64-bit Service Pack 1 logged into a domain. The laptop is a Dell Latitude E6430 and is docked. Process Explorer runs as an administrator and minimized to the tray with CPU, Disk and Network History icons showing.
Occasionally, I will right-click the tray icons and click "Close Process Explorer". The rest of the menu disappears but the "Close Process Explorer" is still on the screen but slightly faded. At this point, the entire machine is frozen. The machine doesn't always freeze, though. Sometimes Process Explorer simply exits without incident.
When the machine is frozen, it is frozen solid. The mouse doesn't move.
Delete don't do anything. It appears the keyboard is completely non-functional. Pressing the power button on the docking station doesn't do anything. Pressing and holding the power button on the docking station for 4-5 seconds shuts off the laptop. When the laptop reboots, Windows complains of an unexpected shutdown.
With the laptop booted up from a complete shutdown (i.e. not sleep or hibernate), I can start and exit Process Explorer several times without freezing the laptop. My laptop has a sleep freeze issue. See this question. If I put the laptop to sleep and wake it up, then exiting Process Explorer will freeze the laptop.