I've used Windows 7 for a long time at home where I never need to search for anything. But now that work has upgraded from XP to 7, I have no idea how to search one particularity drive.
I use Everything to search files on windows. Is faster than the one that comes integrated on the explorer. If you choose to install everything the only thing you have to do is: "Right click" on the drive and then click on "Search with Everything..."
EDIT: Download Everything
I like the keyboard. So I hit Windows+R to bring up the run dialog, and type
cmd, and press Enter.
I then type
dir x:\filename.ext /s /a and press Enter. Replace the
x: with whatever drive letter I want to search, and
filename.ext with the file (or wildcard search) I want to find. The
/s searches all subfolders, and the
/a finds all file/folder types.
None of the answers on this page will work correctly, unless you install the 3rd party app, which also doesn't answer the OP question.
The way you search only one drive, is when you open explorer to the drive you want, you still need to type in the drive letter, colon, and slash in the search box, and use an asterix if you need.
e.g. to find all pictured
If you do this
*.jpg, even though you have clicked on the c drive before you search, it will still dig millions out of D,E, and so forth.