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I have a current version of VirtualBox 4.3.20, but after the latest Windows 7 update on Dec. 11th, 2014, it cannot open any virtual machine. First, it would not open the program at all. After a reboot, it would say:

STATUS_OBJECT_NAME_NOT_FOUND
Driver is probably stuck stopping/starting. Try 'sc.exe query vboxdrv' to get more information about its state. Rebooting may actually help. (rc=-101)
The log file says:
b28.146c: supR3HardenedVmProcessInit: Opening vboxdrv stub...
b28.146c: Error opening VBoxDrvStub: STATUS_OBJECT_NAME_NOT_FOUND
b28.146c: supR3HardenedWinReadErrorInfoDevice: NtCreateFile -> 0xc0000034
b28.146c: Error -101 in supR3HardenedWinReSpawn! (enmWhat=3)
b28.146c: NtCreateFile(\Device\VBoxDrvStub) failed: 0xc0000034 STATUS_OBJECT_NAME_NOT_FOUND (0 retries)
I've tried installing an older version (4.3.18) as well, reinstalling the current version several times, rebooting, uninstalling antivirus software, but nothing helped.
sc start vboxdrvand if that fails findC:\Program Files\Oracle\VirtualBox\drivers\vboxdrv\VBoxDrv.infright click and selectInstalland try again – KCD May 28 '15 at 19:39sc start vboxdrvand now I can use my VM. Make sure to run cmd as administrator, otherwise it won't work. thank you @KCD you saved me – samayo Feb 26 '16 at 11:05