I did use a communication cable which shorted out my DELL Latitude D600 usb ports. at the time I have plugged that cable the screen went black. I did restart the computer but not one of the USB ports are working, It's something can be fixed without replacing the motherboard? Thank you
The USB ports are built-in on the motherboard. Unless you can track and replace the chips, you have to change the whole motherboard.
As an alternative, you can purchase PCMCIA USB card for your laptop.