A reboot seems to fix it, but after logging out (sometimes with the ever-amazing ctrl-alt-backspace, if you can call that logging out) and back in chrome loses audio. The speaker icon on the tab starts, but still no sound. Other apps such as vlc, amarok, paplay etc. work just fine. This seemed to start after updating google-chrome from v39 to v41. I'm using Fedora 21 with KDE. Checking KDE Mixer, there was no google chrome in Playback Streams either.
To narrow down the problem I've killed all chrome windows with
killall chrome and run
google-chrome from the terminal so I can see its output. Heading to an HTML5 audio test page I get this:
ALSA lib pulse.c:243:(pulse_connect) PulseAudio: Unable to connect: Connection refused
I've tried restarting pulse audio with
pulseaudio -k but this doesn't seem to fix anything.
What could the problem be?