As far as I know, Visual Studio must save layouts for, e.g.,
Debug modes apart from each other.
But that's not the case. Toolbars I switch on/off in
Edit are transitioned to
Debug and vice versa. Only Debug, Debug Location and Application Insights toolbars' statuses are saved. May be some others too, I didn't check all of them, but about a half of all, just those that I use, mostly.
Windows layouts are saved as intended, though.
I've reset Environment Settings a couple of times and experimented with opening/closing VS in different modes, but still no signs of solution.