I purchased a Transcend 128GB USB 3.0 flash drive last month. It does not work on the two USB 3.0 ports on my computer, which has an ASUS Rampage III Extreme motherboard. The device doesn't even light up at all. Yet other flash drives (non-3.0) work fine on those ports. An Anker USB 3.0 hub that I just purchased works fine, too.
Plugging that Transcend flash drive into another USB port (2.0, presumably), it lights up and is recognized immediately.