Type in Defender into the search bar, then click the Defender program in the list, when defender opens click settings and turn off real time protection.
I just noticed that it will re enable it automatically after time, geez.
I suppose you will could install some third party AV that does not flag hack tools and the such as a threat.
There is a third party app called NoDefender to disable it permanently but have not tried it or can vouch for it or what it actually does to accomplish this.
I found this note on another website, not sure if it is true or not, better make a restore point anyway.
NOTE: The NoDefender utility doesn’t include an option to enable Windows Defender again. So we suggest you create a manual system restore point before disabling Defender if you want to easily enable Windows Defender again in future.
Another method is to rename the Defender program folder, this must be done from a Linux Live DVD or USB:
C:\Program Files\Windows Defender.
Another method is to disable the Defender Service from starting in the Windows registry as it cannot be done from Services directly as options are grayed out.
Open regedit and go to
Open the subkey corresponding to the service you wish to change (WinDefend), and modify the value of 'Start' to equal either "2" (for automatic), "3" (for manual) or "4" (for disabled)
**Registry edits have the advantage for Windows Home or lower versions, as they do not have Group Policy Editor to do it as suggested by Nate's answer.