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I read this post but there is no Device Settings in my mouse configurations.

How can you reverse the scrolling of mighty mouse in Windows 10?

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    Windows 10 reversed 2-finger scrolling on trackpads and touchscreens. I think you would have to get software from your mouse manufacturer for changes to your mouse wheel behaviour. – HighTechGeek Oct 13 '15 at 20:45
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You can use X-Button Mouse Control and remap the wheel up and wheel down to their opposites. It will also allow you to remap any buttons to other functions system wide, or per program as desired.

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First install AutoHotKey. Now create a script that looks like this :

$WheelUp::
Send {WheelDown}
Return

$WheelDown::
Send {WheelUp}
Return

Save it as a .ahk file and double-click the file to run it. Now you should have inverted the mouse wheel scrolling.

All information from here, though it has been modified with the addition of the $ prefix to prevent the Send commands from being captured again by the script (which exacerbates the MaxHotkeysPerInterval issue)

Add the following to the script to invert horizontal wheel scrolling:

$WheelLeft::
Send {WheelRight}
Return

$WheelRight::
Send {WheelLeft}
Return

Scrolling with the wheel might exceed the default limit of hotkey presses in a specified time interval. By default, this is 70 hotkey presses (#MaxHotkeysPerInterval) per 2000 milliseconds (#HotkeyInterval). Add this directive to your script to increase the limit from 70 to 200 hotkey presses per interval:

#MaxHotkeysPerInterval 200
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