The "News and Interests" taskbar item is always blurry at 100% scaling, independently of the monitor that it's displayed on. This was fixed in a later Windows build 19043.1081 (KB5003690).


Just building up on @harrymc 's answer: Check your HDMI version (before using gtf) by comparing the release date of your board and those of the HDMI versions, just to discard the possibility of having an old version which does not support such resolution with those refresh rates. In my case, probably 1.4b, I lost a lot of time messing with outdated drivers ...

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